{"id":3007,"date":"2023-09-18T11:08:30","date_gmt":"2023-09-18T02:08:30","guid":{"rendered":"https:\/\/misterx95.myds.me\/wordpress\/?page_id=3007"},"modified":"2023-09-22T14:15:08","modified_gmt":"2023-09-22T05:15:08","slug":"post-docs","status":"publish","type":"page","link":"https:\/\/misterx95.myds.me\/wordpress\/?page_id=3007","title":{"rendered":"Post Docs"},"content":{"rendered":"\n<div class=\"wp-block-media-text is-stacked-on-mobile is-vertically-aligned-top\" style=\"grid-template-columns:23% auto\"><figure class=\"wp-block-media-text__media\"><img decoding=\"async\" loading=\"lazy\" width=\"394\" height=\"466\" src=\"https:\/\/misterx95.myds.me\/wordpress\/wp-content\/uploads\/2023\/09\/KakaoTalk_Photo_2023-09-22-13-49-05.jpeg\" alt=\"\" class=\"wp-image-3029 size-full\" srcset=\"https:\/\/misterx95.myds.me\/wordpress\/wp-content\/uploads\/2023\/09\/KakaoTalk_Photo_2023-09-22-13-49-05.jpeg 394w, https:\/\/misterx95.myds.me\/wordpress\/wp-content\/uploads\/2023\/09\/KakaoTalk_Photo_2023-09-22-13-49-05-254x300.jpeg 254w\" sizes=\"(max-width: 394px) 100vw, 394px\" \/><\/figure><div class=\"wp-block-media-text__content\">\n<h2>Dr. Wook-Joo Lee<\/h2>\n\n\n\n<h4><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37201698\/\" target=\"_blank\" rel=\"noreferrer noopener\">FSLLRY-NH<sub>2<\/sub>, a protease-activated receptor 2 (PAR2) antagonist, activates mas-related G protein-coupled receptor C11 (MrgprC11) to induce scratching behaviors in mice.<\/a><\/h4>\n\n\n\n<p>In Kim H, Lee GB, Song DE, Sanjel B, <strong>Lee WJ<\/strong>, Shim WS.Life Sci. 2023 Jul 15;325:121786. doi: 10.1016\/j.lfs.2023.121786. Epub 2023 May 16.PMID:&nbsp;37201698. PMID: 36632132<\/p>\n\n\n\n<h4><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36632132\/\" target=\"_blank\" rel=\"noreferrer noopener\">Rg3-enriched Korean red ginseng alleviates chloroquine-induced itch and dry skin pruritus in an MrgprA3-dependent manner in mice.<\/a><\/h4>\n\n\n\n<p><strong>Lee WJ<\/strong>, Shim WS.Integr Med Res. 2023 Mar;12(1):100916. doi: 10.1016\/j.imr.2022.100916. Epub 2022 Dec 23.PMID:&nbsp;36632132&nbsp;<\/p>\n\n\n\n<h4><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34925342\/\">Cutaneous Neuroimmune Interactions of TSLP and TRPV4 Play Pivotal Roles in Dry Skin-<\/a><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34925342\/\" target=\"_blank\" rel=\"noreferrer noopener\">Induced<\/a><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34925342\/\"> Pruritus.<\/a><\/h4>\n\n\n\n<p><strong>Lee WJ<\/strong>, Shim WS.Front Immunol. 2021 Dec 2;12:772941. doi: 10.3389\/fimmu.2021.772941. eCollection 2021.PMID:&nbsp;34925342&nbsp;<\/p>\n\n\n\n<h4><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32536619\/\" target=\"_blank\" rel=\"noreferrer noopener\">Crotamiton, an Anti-Scabies Agent, Suppresses Histamine- and Chloroquine-Induced Itch Pathways in Sensory Neurons and Alleviates Scratching in Mice.<\/a><\/h4>\n\n\n\n<p>Choi DS, Ji Y, Jang Y, <strong>Lee WJ<\/strong>, Shim WS.Biomol Ther (Seoul). 2020 Nov 1;28(6):569-575. doi: 10.4062\/biomolther.2020.063.PMID:&nbsp;32536619<\/p>\n\n\n\n<h4><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31325512\/\" target=\"_blank\" rel=\"noreferrer noopener\">Extracts of the leaves of Pyrus ussuriensis Maxim. Alleviate itch sensation via TSLP-dependent manner in mouse models of atopic dermatitis.<\/a><\/h4>\n\n\n\n<p>Kim BH, <strong>Lee WJ<\/strong>, Sanjel B, Cho K, Son YK, Park HY, Kim SY, Shim WS.Physiol Behav. 2019 Oct 15;210:112624. doi: 10.1016\/j.physbeh.2019.112624. Epub 2019 Jul 17.PMID:&nbsp;3132551<\/p>\n\n\n\n<h4><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30337807\/\" target=\"_blank\" rel=\"noreferrer noopener\">Korean Red Ginseng extract and ginsenoside Rg3 have anti-pruritic effects on chloroquine-induced itch by inhibition of MrgprA3\/TRPA1-mediated pathway.<\/a><\/h4>\n\n\n\n<p><strong>Lee WJ<\/strong>, Kim YS, Shim WS.J Ginseng Res. 2018 Oct;42(4):470-475. doi: 10.1016\/j.jgr.2017.05.004. Epub 2017 May 18.PMID:\u00a030337807<\/p>\n\n\n\n<h4><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29432788\/\" target=\"_blank\" rel=\"noreferrer noopener\">Different perception levels of histamine-induced itch sensation in young adult mice.<\/a><\/h4>\n\n\n\n<p>Ji Y, Jang Y, <strong>Lee WJ<\/strong>, Yang YD, Shim WS.Physiol Behav. 2018 May 1;188:188-193. doi: 10.1016\/j.physbeh.2018.02.015. Epub 2018 Feb 9.PMID:\u00a029432788<\/p>\n\n\n\n<h4><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26459162\/\" target=\"_blank\" rel=\"noreferrer noopener\">A novel synthetic Piper amide derivative NED-180 inhibits hyperpigmentation by activating the PI3K and ERK pathways and by regulating Ca2+ influx via TRPM1 channels.<\/a><\/h4>\n\n\n\n<p>Hwang E, Lee TH, <strong>Lee WJ<\/strong>, Shim WS, Yeo EJ, Kim S, Kim SY.Pigment Cell Melanoma Res. 2016 Jan;29(1):81-91. doi: 10.1111\/pcmr.12430.PMID:\u00a026459162<\/p>\n\n\n\n<h4><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26199558\/\" target=\"_blank\" rel=\"noreferrer noopener\">Red ginseng extract blocks histamine-dependent itch by inhibition of H1R\/TRPV1 pathway in sensory neurons.<\/a><\/h4>\n\n\n\n<p>Jang Y, <strong>Lee WJ<\/strong>, Hong GS, Shim WS.J Ginseng Res. 2015 Jul;39(3):257-64. doi: 10.1016\/j.jgr.2015.01.004. Epub 2015 Jan 22.PMID:\u00a026199558<\/p>\n\n\n\n<h4><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24909729\/\" target=\"_blank\" rel=\"noreferrer noopener\">Upregulation of COX-2 in the lung cancer promotes overexpression of multidrug resistance protein 4 (MRP4) via PGE2-dependent pathway.<\/a><\/h4>\n\n\n\n<p>Maeng HJ, <strong>Lee WJ<\/strong>, Jin QR, Chang JE, Shim WS.Eur J Pharm Sci. 2014 Oct 1;62:189-96. doi: 10.1016\/j.ejps.2014.05.023. Epub 2014 Jun 5.PMID:\u00a024909729<\/p>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-media-text is-stacked-on-mobile is-vertically-aligned-top\" style=\"grid-template-columns:23% auto\"><figure class=\"wp-block-media-text__media\"><img decoding=\"async\" loading=\"lazy\" width=\"464\" height=\"550\" src=\"https:\/\/misterx95.myds.me\/wordpress\/wp-content\/uploads\/2023\/09\/KakaoTalk_Photo_2023-09-22-13-42-23.png\" alt=\"\" class=\"wp-image-3025 size-full\" srcset=\"https:\/\/misterx95.myds.me\/wordpress\/wp-content\/uploads\/2023\/09\/KakaoTalk_Photo_2023-09-22-13-42-23.png 464w, https:\/\/misterx95.myds.me\/wordpress\/wp-content\/uploads\/2023\/09\/KakaoTalk_Photo_2023-09-22-13-42-23-253x300.png 253w\" sizes=\"(max-width: 464px) 100vw, 464px\" \/><\/figure><div class=\"wp-block-media-text__content\">\n<h2>Dr. Sanjel Babina<\/h2>\n\n\n\n<h4><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37201698\/\" target=\"_blank\" rel=\"noreferrer noopener\">FSLLRY-NH<sub>2<\/sub>, a protease-activated receptor 2 (PAR2) antagonist, activates mas-related G protein-coupled receptor C11 (MrgprC11) to induce scratching behaviors in mice.<\/a><\/h4>\n\n\n\n<p>In Kim H, Lee GB, Song DE, <strong>Sanjel B<\/strong>, Lee WJ, Shim WS.Life Sci. 2023 Jul 15;325:121786. doi: 10.1016\/j.lfs.2023.121786. Epub 2023 May 16.PMID:&nbsp;37201698<\/p>\n\n\n\n<h4><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35843300\/\" target=\"_blank\" rel=\"noreferrer noopener\">The contribution of mouse models to understanding atopic dermatitis.<\/a><\/h4>\n\n\n\n<p><strong>Sanjel B<\/strong>, Shim WS.Biochem Pharmacol. 2022 Sep;203:115177. doi: 10.1016\/j.bcp.2022.115177. Epub 2022 Jul 14.PMID:&nbsp;35843300&nbsp;Review.&nbsp;PMID: 34766332<\/p>\n\n\n\n<h4><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34766332\/\" target=\"_blank\" rel=\"noreferrer noopener\">Glucosylsphingosine evokes pruritus via activation of 5-HT<sub>2A<\/sub>&nbsp;receptor and TRPV4 in sensory neurons.<\/a><\/h4>\n\n\n\n<p><strong>Sanjel B<\/strong>, Kim BH, Song MH, Carstens E, Shim WS.Br J Pharmacol. 2022 May;179(10):2193-2207. doi: 10.1111\/bph.15733. Epub 2022 Feb 4.PMID:&nbsp;34766332<\/p>\n\n\n\n<h4><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32896605\/\" target=\"_blank\" rel=\"noreferrer noopener\">Recent advances in understanding the molecular mechanisms of cholestatic pruritus: A review.<\/a><\/h4>\n\n\n\n<p><strong>Sanjel B<\/strong>, Shim WS.Biochim Biophys Acta Mol Basis Dis. 2020 Dec 1;1866(12):165958. doi: 10.1016\/j.bbadis.2020.165958. Epub 2020 Sep 5.PMID:&nbsp;32896605&nbsp;Free article.&nbsp;Review. PMID: 31350433<\/p>\n\n\n\n<h4><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31350433\/\" target=\"_blank\" rel=\"noreferrer noopener\">BAM8-22 and its receptor MRGPRX1 may attribute to cholestatic pruritus.<\/a><\/h4>\n\n\n\n<p><strong>Sanjel B<\/strong>, Maeng HJ, Shim WS.Sci Rep. 2019 Jul 26;9(1):10888. doi: 10.1038\/s41598-019-47267-5.PMID:\u00a031350433<\/p>\n<\/div><\/div>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dr. Wook-Joo Lee FSLLRY-NH2, a protease-activated receptor 2 (PAR2) antagonist, activates mas-related G protein-coupled receptor C11 (MrgprC11) to induce scratching behaviors in mice. In Kim H, Lee GB, Song DE, Sanjel B, Lee WJ, Shim WS.Life Sci. 2023 Jul 15;325:121786. doi: 10.1016\/j.lfs.2023.121786. Epub 2023 May 16.PMID:&nbsp;37201698. PMID: 36632132 Rg3-enriched Korean red ginseng alleviates chloroquine-induced itch [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"_links":{"self":[{"href":"https:\/\/misterx95.myds.me\/wordpress\/index.php?rest_route=\/wp\/v2\/pages\/3007"}],"collection":[{"href":"https:\/\/misterx95.myds.me\/wordpress\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/misterx95.myds.me\/wordpress\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/misterx95.myds.me\/wordpress\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/misterx95.myds.me\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3007"}],"version-history":[{"count":5,"href":"https:\/\/misterx95.myds.me\/wordpress\/index.php?rest_route=\/wp\/v2\/pages\/3007\/revisions"}],"predecessor-version":[{"id":3032,"href":"https:\/\/misterx95.myds.me\/wordpress\/index.php?rest_route=\/wp\/v2\/pages\/3007\/revisions\/3032"}],"wp:attachment":[{"href":"https:\/\/misterx95.myds.me\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3007"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}