{"id":2939,"date":"2023-07-15T12:00:00","date_gmt":"2023-07-15T12:00:00","guid":{"rendered":"https:\/\/misterx95.myds.me\/wordpress\/?p=2939"},"modified":"2023-07-15T12:00:00","modified_gmt":"2023-07-15T12:00:00","slug":"molecules-that-channel-stimulus-into-pruritus","status":"publish","type":"post","link":"https:\/\/misterx95.myds.me\/wordpress\/?p=2939","title":{"rendered":"Molecules That Channel Stimulus into Pruritus"},"content":{"rendered":"

Babina Sanjel, Won-Sik Shim: <\/span> Molecules That Channel Stimulus into Pruritus<\/span>. In: <\/span> Tsagareli, Merab G.; Follansbee, Taylor (Ed.): Histaminergic and Non-Histaminergic Itch: From Channels to Behavior, <\/span>Nova Science, <\/span>2023<\/span>, ISBN: 979-8-88697-757-8<\/span>.<\/span><\/div><\/p>\n

Abstract<\/h2>

Pruritus, a sensation that evokes a desire to scratch, is triggered by molecular cascades that result in the excitation of sensory neurons. In general, pruritogens or itch-inducing agents can induce alterations in the membrane potential, coordinated by the actions of distinctive molecules known as ion channels. These specialized molecules are membrane proteins that form distinct pores, through which specific ions can selectively flow when opened. To date, numerous ion channels have been discovered that are involved in the generation and\/or transmission of pruritic signals in the vicinity of the skin. This chapter will summarize representative ion channels that play fundamental roles in pruritus.<\/p>\n

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