{"id":716,"date":"2014-05-17T18:15:55","date_gmt":"2014-05-17T09:15:55","guid":{"rendered":"http:\/\/misterx95.myds.me\/?p=716"},"modified":"2014-05-17T18:15:55","modified_gmt":"2014-05-17T09:15:55","slug":"journal-club-2014-05-24","status":"publish","type":"post","link":"https:\/\/misterx95.myds.me\/wordpress\/?p=716","title":{"rendered":"Journal Club 2014-05-24"},"content":{"rendered":"
Acta Derm Venereol.<\/a>\u00a02014 Mar 7. doi: 10.2340\/00015555-1834. [Epub ahead of print]<\/div>\n

Surfactant-induced Chronic\u00a0Pruritus: Role of L-Histidine Decarboxylase Expression and Histamine Production in Epidermis.<\/h1>\n
Inami Y<\/a>,\u00a0Sasaki A<\/a>,\u00a0Andoh T<\/a>,\u00a0Kuraishi Y<\/a>.<\/div>\n
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\r\n\t\r\n\t\t\"4143\"\r\n\t<\/a>\r\n<\/dt>\r\n
\r\n\tFilename<\/strong> : 4143.pdf<\/a> (408 KB)\r\n\t
\r\n\tCaption<\/strong> : \r\n<\/dd>\r\n<\/dl>

<\/p><\/div><\/a><\/h3>\n

Abstract<\/h3>\n
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Shampoo and cleansers containing anionic surfactants including sodium dodecyl sulphate (SDS) often causepruritus\u00a0in humans. Daily application of 1-10% SDS for 4 days induced hind-paw scratching (an\u00a0itch-related behaviour) in a concentration-dependent manner, and 10% SDS also caused dermatitis, skin dryness, barrier disruption, and an increase in skin surface pH in mice. SDS-induced scratching was inhibited by the opioid receptor antagonist naloxone and the H1 histamine receptor antagonist terfenadine. Mast-cell deficiency did not inhibit SDS-induced scratching, although it almost completely depleted histamine in the dermis. Treatment with SDS increased the histamine content of the epidermis, but not that of the dermis. SDS treatment increased the gene expression and post-translation processing of L-histidine decarboxylase in the epidermis. The present results suggest that repeated application of SDS induces\u00a0itch\u00a0through increased production of epidermal histamine, which results from an increase in the gene expression and post-translation processing of L-histidine decarboxylase.<\/p>\n<\/div>\n<\/div>\n

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PMID:\u00a024603881<\/dt>\n<\/dl>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Acta Derm Venereol.\u00a02014 Mar 7. doi: 10.2340\/00015555-1834. [Epub ahead of print] Surfactant-induced Chronic\u00a0Pruritus: Role of L-Histidine Decarboxylase Expression and Histamine Production in Epidermis. Inami Y,\u00a0Sasaki A,\u00a0Andoh T,\u00a0Kuraishi Y. Abstract Shampoo and cleansers containing anionic surfactants including sodium dodecyl sulphate (SDS) often causepruritus\u00a0in humans. Daily application of 1-10% SDS for 4 days induced hind-paw scratching (an\u00a0itch-related […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/misterx95.myds.me\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/716"}],"collection":[{"href":"https:\/\/misterx95.myds.me\/wordpress\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/misterx95.myds.me\/wordpress\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/misterx95.myds.me\/wordpress\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/misterx95.myds.me\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=716"}],"version-history":[{"count":1,"href":"https:\/\/misterx95.myds.me\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/716\/revisions"}],"predecessor-version":[{"id":718,"href":"https:\/\/misterx95.myds.me\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/716\/revisions\/718"}],"wp:attachment":[{"href":"https:\/\/misterx95.myds.me\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=716"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/misterx95.myds.me\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=716"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/misterx95.myds.me\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=716"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}