New mechanism underlying IL-31-induced atopic dermatitis.
Abstract
BACKGROUND:
TH2 cell-released IL-31 is a critical mediator in patients with atopic dermatitis (AD), a prevalent and debilitating chronic skin disorder. Brain-derived natriuretic peptide (BNP) has been described as a central itch mediator. The importance of BNP in peripheral (skin-derived) itch and its functional link to IL-31 within the neuroimmune axis of the skin is unknown.
-
-
Filename : 1-s2-0-s0091674918302148-main.pdf (6 MB)
Caption :